|Source: Wikimedia Commons.|
Along with other artifacts found on the island including makeup and glass bottles, a DNA confirmation that the bones belong to Earhart would finally put to rest the mystery of what happened to her. If the bones are Earhart it would be valid to conclude that her plane crashed, and that she survived as a castaway for some time before dying on the island.
If DNA can give an ending to the story of Amelia Earhart, it will definitely be a win for genetics, and scientific research in general. The question that would be left (at least for me) is what happened to her plane (or her navigator for that matter)?